sito web:Per favore aspetta... Clouddichiaratosoddisfare
MDPI-PublisherofOpenAccessJournals(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':newDate().getTime(),event:'gtm.js'});varf=d.getElementsByTName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-WPK7SW5');_linkedin_partner_id="";window._linkedin_data_partner_ids=window._linkedin_data_partner_ids||[];window._linkedin_data_partner_ids.push(_linkedin_partner_id);(function(){vars=document.getElementsByTName("script")[0];varb=document.createElement("script");b.type="text/jascript";b.async=true;b.src="snap.licdn.com/li.lms-analytics/insight.min.js";s.parentNode.insertBefore(b,s);})();JournalsActiveJournalsFindaJournalJournalProposalProceedingsSeriesTopicsInformationForAuthorsForReviewersForEditorsForLibrariansForPublishersForSocietiesForConferenceOrganizersOpenAccessPolicyInstitutionalOpenAccessProgramSpecialIssuesGuidelinesEditorialProcessResearchandPublicationEthicsArticleProcessingChargesAwardsTestimonialsEditingServicesInitiativesSciforumMDPIBooksPreprints.orgScilitSciProfilesEncyclopediaJAMSProceedingsSeriesAboutOverviewContactCareersNewsPressBlogSignIn/SignUpNoticeYoucanmakesubmissionstootherjournalshere.clearNoticeYouareaccessingamachine-readablepe.Inordertobehuman-readable,pleaseinstallanRSSreader.ContinueCancelclearAllarticlespublishedbyMDPIaremadeimmediatelyailableworldwideunderanopenaccesslicense.NospecialpermissionisrequiredtoreuseallorpartofthearticlepublishedbyMDPI,includingfiguresandtables.ForarticlespublishedunderanopenaccessCreativeCommonCCBYlicense,anypartofthearticlemaybereusedwithoutpermissionprovidedthattheoriginalarticleisclearlycited.Formoreinformation,pleasereferto/openaccess.Featurepapersrepresentthemostadvancedresearchwithsignificantpotentialforhighimpactinthefield.AFeaturePapershouldbeasubstantialoriginalArticlethatinvolvesseveraltechniquesorapproaches,providesanoutlookforfutureresearchdirectionsanddescribespossibleresearchapplications.Featurepapersaresubmitteduponindividualinvitationorrecommendationbythescientificeditorsandmustreceivepositivefeedbackfromthereviewers.Editor’sChoicearticlesarebasedonrecommendationsbythescientificeditorsofMDPIjournalsfromaroundtheworld.Editorsselectasmallnumberofarticlesrecentlypublishedinthejournalthattheybelievewillbeparticularlyinterestingtoreaders,orimportantintherespectiveresearcharea.Theaimistoprovideasnapshotofsomeofthemostexcitingworkpublishedinthevariousresearchareasofthejournal.OriginalSubmissionDateReceived:.Youseemtohejascriptdisabled.Pleasenotethatmanyofthepefunctionalitieswon'tworkasexpectedwithoutjascriptenabled.clearzoom_out_mapsearchmenu JournalsActiveJournalsFindaJournalJournalProposalProceedingsSeriesTopicsInformationForAuthorsForReviewersForEditorsForLibrariansForPublishersForSocietiesForConferenceOrganizersOpenAccessPolicyInstitutionalOpenAccessProgramSpecialIssuesGuidelinesEditorialProcessResearchandPublicationEthicsArticleProcessingChargesAwardsTestimonialsEditingServicesInitiativesSciforumMDPIBooksPreprints.orgScilitSciProfilesEncyclopediaJAMSProceedingsSeriesAboutOverviewContactCareersNewsPressBlogSignIn/SignUpSubmitAdvancingOpenScienceformorethan25yearsSupportingacademiccommunitiessince1996 SearchforArticles:Title/KeywordAuthor/Affiliation/EmailJournalAllJournalsAcousticsActaMicrobiologicaHellenica(AMH)ActuatorsAdministrativeSciencesAdolescentsAdvancesinRespiratoryMedicine(ARM)AerobiologyAerospacericultureriEngineeringrochemicalsronomyAIAirAlgorithmsAllergiesAlloysAnalyticaAnalyticsAnatomiaAnesthesiaResearchAnimalsAntibioticsAntibodiesAntioxidantsAppliedBiosciencesAppliedMechanicsAppliedMicrobiologyAppliedNanoAppliedSciencesAppliedSystemInnovation(ASI)AppliedChemAppliedMathAquacultureJournalArchitectureArthropodaArtsAstronomyAtmosphereAtomsAudiologyResearchAutomationAxiomsBacteriaBatteriesBehioralSciencesBeveresBigDataandCognitiveComputing(BDCC)BioChemBioengineeringBiologicsBiologyBiologyandLifeSciencesForumBiomassBiomechanicsBioMedBiomedicinesBioMedInformaticsBiomimeticsBiomoleculesBiophysicaBiosensorsBioTechBirdsBlockchainsBrainSciencesBuildingsBusinessesCCancersCardiogeneticsCatalystsCellsCeramicsChallengesChemEngineeringChemistryChemistryProceedingsChemosensorsChildrenChipsCivilEngCleanTechnologies(CleanTechnol.)ClimateClinicalandTranslationalNeuroscience(CTN)ClinicalBioenergeticsClinicsandPracticeClocks&SleepCoastsCoatingsColloidsandInterfacesColorantsCommoditiesComplicationsCompoundsComputationComputerSciences&MathematicsForumComputersCondensedMatterConservationConstructionMaterialsCorrosionandMaterialsDegradation(CMD)CosmeticsCOVIDCropsCryoCryptographyCrystalsCurrentIssuesinMolecularBiology(CIMB)CurrentOncologyDairyDataDentistryJournalDermatoDermatopathologyDesignsDiabetologyDinosticsDieteticsDigitalDisabilitiesDiseasesDiversityDNADronesDrugsandDrugCandidates(DDC)DynamicsEarthEcologiesEconometricsEconomiesEducationSciencesElectricityElectrochemElectronicMaterialsElectronicsEmergencyCareandMedicineEncyclopediaEndocrinesEnergiesEnergyStoreandApplications(ESA)EngEngineeringProceedingsEntropyEnvironmentalandEarthSciencesProceedingsEnvironmentsEpidemiologiaEpigenomesEuropeanBurnJournal(EBJ)EuropeanJournalofInvestigationinHealth,PsychologyandEducation(EJIHPE)FermentationFibersFinTechFireFishesFluidsFoodsForecastingForensicSciencesForestsFossilStudiesFoundationsFractalandFractional(FractalFract)FuelsFutureFutureInternetFuturePharmacologyFutureTransportationGalaxiesGamesGasesGastroenterologyInsightsGastrointestinalDisordersGastronomyGelsGenealogyGenesGeographiesGeoHazardsGeomaticsGeometryGeosciencesGeotechnicsGeriatricsGlaciesGout,Urate,andCrystalDepositionDisease(GUCDD)GrassesHardwareHealthcareHeartsHematoHematologyReportsHeriteHistoriesHorticulturaeHospitalsHumanitiesHumansHydrobiologyHydrogenHydrologyHygieneImmunoInfectiousDiseaseReportsInformaticsInformationInfrastructuresInorganicsInsectsInstrumentsIntelligentInfrastructureandConstructionInternationalJournalofEnvironmentalResearchandPublicHealth(IJERPH)InternationalJournalofFinancialStudies(IJFS)InternationalJournalofMolecularSciences(IJMS)InternationalJournalofNeonatalScreening(IJNS)InternationalJournalofPlantBiology(IJPB)InternationalJournalofTopologyInternationalJournalofTranslationalMedicine(IJTM)InternationalJournalofTurbomachinery,PropulsionandPower(IJTPP)InternationalMedicalEducation(IME)InventionsIoTISPRSInternationalJournalofGeo-Information(IJGI)JJournalofeingandLongevity(JAL)JournalofCardiovascularDevelopmentandDisease(JCDD)JournalofClinical&TranslationalOphthalmology(JCTO)JournalofClinicalMedicine(JCM)JournalofCompositesScience(J.Compos.Sci.)JournalofCybersecurityandPrivacy(JCP)JournalofDementiaandAlzheimer039;sDisease(JDAD)JournalofDevelopmentalBiology(JDB)JournalofExperimentalandTheoreticalAnalyses(JETA)JournalofFunctionalBiomaterials(JFB)JournalofFunctionalMorphologyandKinesiology(JFMK)JournalofFungi(JoF)JournalofIming(J.Iming)JournalofIntelligence(J.Intell.)JournalofLowPowerElectronicsandApplications(JLPEA)JournalofManufacturingandMaterialsProcessing(JMMP)JournalofMarineScienceandEngineering(JMSE)JournalofMarketAccess&HealthPolicy(JMAHP)JournalofMolecularPathology(JMP)JournalofNanotheranostics(JNT)JournalofNuclearEngineering(JNE)JournalofOtorhinolaryngology,HearingandBalanceMedicine(JOHBM)JournalofParksJournalofPersonalizedMedicine(JPM)JournalofPharmaceuticalandBioTechIndustry(JPBI)JournalofRespiration(JoR)JournalofRiskandFinancialManement(JRFM)JournalofSensorandActuatorNetworks(JSAN)JournaloftheOmanMedicalAssociation(JOMA)JournalofTheoreticalandAppliedElectronicCommerceResearch(JTAER)JournalofVascularDiseases(JVD)JournalofXenobiotics(JoX)JournalofZoologicalandBotanicalGardens(JZBG)JournalismandMediaKidneyandDialysisKinasesandPhosphatasesKnowledgeLabMedLaboratoriesLandLanguesLawsLifeLimnologicalReviewLipidologyLiquidsLiteratureLiversLogicsLogisticsLubricantsLymphaticsMachineLearningandKnowledgeExtraction(MAKE)MachinesMacromolMnetismMnetochemistryMarineDrugsMaterialsMaterialsProceedingsMathematicalandComputationalApplications(MCA)MathematicsMedicalSciencesMedicalSciencesForumMedicinaMedicinesMembranesMeritsMetabolitesMetalsMeteorologyMethaneMethodsandProtocols(MPs)MetricsMetrologyMicroMicrobiologyResearchMicromachinesMicroorganismsMicroplasticsMineralsMiningModellingModernMathematicalPhysicsMolbankMoleculesMultimodalTechnologiesandInteraction(MTI)MusclesNanoenergyAdvancesNanomanufacturingNanomaterialsNDTNetworkNeurogliaNeurologyInternationalNeuroSciNitrogenNon-CPer favore aspetta... ClouddichiaratoodingRNA(ncRNA)NursingReportsNutraceuticalsNutrientsObesitiesOceansOncoOpticsOralOrganicsOrganoidsOsteologyOxygenParasitologiaParticlesPathogensPathophysiologyPediatricReportsPetsPharmaceuticalsPharmaceuticsPharmacoepidemiologyPharmacyPhilosophiesPhotochemPhotonicsPhycologyPhyschemPhysicalSciencesForumPhysicsPhysiologiaPlantsPlasmaPlatformsPollutantsPolymersPolysaccharidesPopulationsPoultryPowdersProceedingsProcessesProsthesisProteomesPsychiatryInternationalPsychoactivesPsychologyInternationalPublicationsQuantumBeamScience(QuBS)QuantumReportsQuaternaryRadiationReactionsRealEstateReceptorsRecyclingRegionalScienceandEnvironmentalEconomics(RSEE)ReligionsRemoteSensingReportsReproductiveMedicine(Reprod.Med.)ResourcesRheumatoRisksRoboticsRuminantsSafetySciScientiaPharmaceutica(Sci.Pharm.)SclerosisSeedsSensorsSeparationsSexesSignalsSinusitisSmartCitiesSocialSciencesSociétéInternationaled’UrologieJournal(SIUJ)SocietiesSoftwareSoilSystemsSolarSolidsSpectroscopyJournalSportsStandardsStatsStressesSurfacesSurgeriesSurgicalTechniquesDevelopmentSustainabilitySustainableChemistrySymmetrySynBioSystemsTargetsTaxonomyTechnologiesTelecomTextilesThalassemiaReportsTherapeuticsThermoTimeandSpaceTomographyTourismandHospitalityToxicsToxinsTransplantologyTraumaCareTrendsinHigherEducationTropicalMedicineandInfectiousDisease(TropicalMed)UniverseUrbanScienceUroVaccinesVehiclesVenereologyVeterinarySciencesVibrationVirtualWorldsVirusesVisionWasteWaterWildWindWomenWorldWorldElectricVehicleJournal(WEVJ)YouthZoonoticDiseasesArticleTypeAllArticleTypesArticleReviewCommunicationEditorialAbstractBookReviewBriefCommunicationBriefReportCaseReportClinicopathologicalChallengeCommentCommentaryConceptPaperConferenceReportCorrectionCreativeDataDescriptorDiscussionEntryEssayExpressionofConcernExtendedAbstractFieldGuideGuidelinesHypothesisInterestingImesLetterNewBookReceivedObituaryOpinionPerspectiveProceedingPaperProjectReportProtocolRegisteredReportReplyRetractionShortNoteStudyProtocolSystematicReviewTechnicalNoteTutorialViewpoint AdvancedSearch SectionSpecialIssueVolumeIssueNumberPe LogicalOperatorOperatorANDORSearchTextSearchTypeAllfieldsTitleAbstractKeywordsAuthorsAffiliationsDoiFullTextReferences add_circle_outlineremove_circle_outline //AtomsGordonDecompositionoftheMnetizabilityofaDiracOne-ElectronAtominanArbitraryDiscreteEnergyStateCatalystsRecentAdvancesinPhotocatalyticDegradationofTetracyclineAntibioticsAxiomsOnaGenericFractionalDerivativeAssociatedwiththeRiemann–LiouvilleFractionalIntegralAnimalsNativeComparedtoCitratedWholeBloodforCoulationTestinginHorsesNutrientsEggConsumptionand4-YearChangeinCognitiveFunctioninOlderMenandWomenRecentArticles 11pes,283KiB OpenAccessArticleAssociationsofDepressionScorewithDialkylPhosphateMetabolitesinUrine:ACross-SectionalStudybyHaiZhaoandXuejunKangBrainSci.2024,14(12),1290;doi.org/10.3390/brainsci(registering DOI)-21Dec2024AbstractObjectives:Growingevidencesuggestsalinkbetweenorganophosphateinsecticidesanddepressiondisorder.Thesechemicalsaremetabolizedandsubsequentlyexpelledthroughtheurinarytract.Thepresentstudyaimstoinvestigatewhetherdialkylphosphatemetabolitesassociatewithdepressionscoreandseverityamongthegeneralpopulation.[...]Readmore.Objectives:Growingevidencesuggestsalinkbetweenorganophosphateinsecticidesanddepressiondisorder.Thesechemicalsaremetabolizedandsubsequentlyexpelledthroughtheurinarytract.Thepresentstudyaimstoinvestigatewhetherdialkylphosphatemetabolitesassociatewithdepressionscoreandseverityamongthegeneralpopulation.Methods:Thiscross-sectionalstudyuseddatafromtheNationalHealthandNutritionExaminationSurvey(NHANES).DepressionwasevaluatedbythePatientHealthQuestionnaire-9(PHQ-9).Allurinarydialkylphosphatemetaboliteswerequantitativelyanalyzed.Thesurvey’scomplexdesignparametersandsamplingweightswereconsidered.Results:3035eligibleindividualswereincluded.Theestimatedprevalenceofmildandmajordepressionwas18.3%(95%confidenceinterval[CI]:16.9–19.7%)and9.9%(95%CI:8.7–11.0%).Foreachincrementalunitinthelevelofurinarydimethylphosphate(DMP),individualswerefoundtoheahigherdepressionscoreof0.77andasignificantlyincreasedoddsratio(OR)of1.13(95%CI:1.12–1.13)formilddepressionand2.75(95%CI:2.74–2.76)formajordepression.Conclusions:Ourfindingsindicatepositiveandindependentassociationsbetweenurinarydialkylphosphatemetabolitesandanelevatedriskofdepressionamongthegeneralpopulation.Fullarticle(ThisarticlebelongstotheSectionPsychiatricDiseases)23pes,3211KiB OpenAccessArticleIntegrativeFrameworkforDecodingSpatialandTemporalDriversofLandUseChangeinMalaysia:StrategicInsightsforSustainableLandManementbyGuanqiongYe,KehaoChen,YiqunYang,ShanshanLiang,WenjiaHuandLiuyueHeLand2024,13(12),2248;doi.org/10.3390/land(registering DOI)-21Dec2024AbstractIdentifyingthedriversoflanduseandcoverchange(LUCC)iscrucialforsustainablelandmanement.However,understandingspatialdifferentiationandconductinginter-regionalcomparisonsofthesedriversremainslimited,particularlyinregionslikeMalaysia,wherecomplexinteractionsbetweenhumanactivitiesandnaturalconditions[...]Readmore.Identifyingthedriversoflanduseandcoverchange(LUCC)iscrucialforsustainablelandmanement.However,understandingspatialdifferentiationandconductinginter-regionalcomparisonsofthesedriversremainslimited,particularlyinregionslikeMalaysia,wherecomplexinteractionsbetweenhumanactivitiesandnaturalconditionsposesignificantchallenges.ThisstudypresentsanovelanalyticalframeworktoexaminethespatialvariationsandcomplexitiesofLUCC,specificallyaddressingthespatiotemporalpatterns,drivingfactors,andpathwaysofLUCCinMalaysiafrom2010to2020.Integratingthelandusetransfermatrix,GeoDetectormodel,andStructuralEquationModeling(SEM),werevealasignificantexpansionoffarmlandandurbanareasalongsideadeclineinforestcover,withnotableregionalvariationsinMalaysia.Human-drivenfactors,suchaspopulationgrowthandeconomicdevelopment,areidentifiedastheprimaryforcesbehindthesechanges,outweighingtheinfluenceofnaturalconditions.Critically,theinteractionsamongthesedriversexertastrongerinfluenceonLUCCdynamicsinMalaysiathananysinglefactoralone,suggestingincreasinglycomplexLUCCpredictionsinthefuture.Thiscomplexityemphasizestheurgencyofproactive,multifaceted,andregion-specificlandmanementpoliciestopreventirreversibleenvironmentaldegradation.ByproposingtailoredlandmanementstrategiesforMalaysia’sfivesubnationalregions,thisstudyaddressesspatialvariationsindriversandclimateresilience,offeringastrategicblueprintfortimelyactionthatcanbenefitMalaysiaandotherregionsfacingsimilarchallengesinsustainablelandmanement.Fullarticle(ThisarticlebelongstotheSpecialIssueLandUse/CoverChangeandItsImpactsonRegionalSustainableDevelopment)37pes,4111KiB OpenAccessArticleUrbanGreenInfrastructuresasToolsforUrbanInterconnection:TheCaseofSanBartolomeoDistrictinCliari,ItalybyLuigiMundula,ClaraDiFazio,FrancescaLeccisandMariaParadisoSustainability2024,16(24),;doi.org/10.3390/su6(registering DOI)-21Dec2024AbstractContemporaryurbanareasareoftencharacterizedbyvariousformsofencles,isolatedfromtheirsurroundinggeographicalcontext.Urbangreeninfrastructuresprovideanopportunitytoopentheseencles,establishingphysicalandfunctionalconnectionswiththebroadercity,whilealsocontributingtoclimatechangemitigation[...]Readmore.Contemporaryurbanareasareoftencharacterizedbyvariousformsofencles,isolatedfromtheirsurroundinggeographicalcontext.Urbangreeninfrastructuresprovideanopportunitytoopentheseencles,establishingphysicalandfunctionalconnectionswiththebroadercity,whilealsocontributingtoclimatechangemitigationandadaptation.ThisstudyexaminesthedistrictofSanBartolomeointheItaliancityofCliariasanexampleofanurbanencle,andemploysaparticipatoryplanningprocesstodesignaprojectthattransformsitintoahubopentothewidercitycommunity.Theresultisaneighborhoodshapedbyitscommunity,wheresocial,economic,andenvironmentalneedsarebalanced,fosteringconstantinteractionbetweenresidentsandthecityasawhole.Fullarticle(ThisarticlebelongstotheSpecialIssueASystemsApproachtoUrbanGreenspaceSystemandClimateChange)25pes,889KiB OpenAccessReviewRecyclingLithium-IonBatteries—Technologies,Environmental,HumanHealth,andEconomicIssues—Mini-SystematicLiteratureReviewbyGeaniTeodorMan,AndreeaMariaIordache,RamonaZgarogeaandConstantinNechitaMembranes2024,14(12),277;doi.org/10.3390/membranes(registering DOI)-21Dec2024AbstractGlobalconcernsaboutpollutionreduction,associatedwiththecontinuoustechnologicaldevelopmentofelectronicequipmentraiseschallengeforthefutureregardinglithium-ionbatteriesexploitation,use,andrecoverythroughrecyclingofcriticalmetals.Severalhumanandenvironmentalissuesarereported,includingrelateddiseasescausedby[...]Readmore.Globalconcernsaboutpollutionreduction,associatedwiththecontinuoustechnologicaldevelopmentofelectronicequipmentraiseschallengeforthefutureregardinglithium-ionbatteriesexploitation,use,andrecoverythroughrecyclingofcriticalmetals.Severalhumanandenvironmentalissuesarereported,includingrelateddiseasescausedbylithiumwaste.LithiuminLi-ionbatteriescanberecoveredthroughvariousmethodstopreventenvironmentalcontamination,andLicanbereusedasarecyclableresource.Classicaltechnologiesforrecoveringlithiumfrombatteriesareassociatedwithvariousenvironmentalissues,solithiumrecoveryremainschallenging.However,theemergenceofmembraneprocesseshasopenednewresearchdirectionsinlithiumrecovery,offeringhopeformoreefficientandenvironmentallyfriendlysolutions.Theseprocessescanbeintegratedintocurrentindustrialrecyclingflows,hingahighrecoverypotentialandpingthewayforamoresustainablefuture.Asecondmethod,biolexivation,iseco-friendly,butthispointillustratessignificantdrawbackswhenusedonanindustrialscale.WediscussedtoxicityinducedbymetalsassociatedwithLitoiron-oxidizingbacteria,whichneedsfurtherstudysinceitcauseslowrecyclingefficiency.OnemajorenvironmentalproblemisthelowefficiencyoftherecoveryofLifromthewatercycle,whichaffectsglobal-scalesafety.Still,electromembranescanofferpromisingsolutionsinthefuture,butthereisneededtoupdateregulationstoactualneedsforbothproducingandrecyclingLIB.Fullarticle(ThisarticlebelongstotheSectionMembraneApplicationsforEnergy)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,731KiB)16pes,3290KiB OpenAccessArticleCmpk2GeneandProteinExpressioninSalivaorSalivaryGlandsofDyslipidemicMicebyBaiyanZhang,AkiyoKawamoto,MasatoNakawa,YoshitomoHondaandKazuyaTakahashiAppl.Sci.2024,14(24),;doi.org/10.3390/app4(registering DOI)-21Dec2024AbstractSalivarybiomarkersarepromisingmoleculesfordinosingsystemicdiseases.Cytidine/uridinemonophosphatekinase2(CMPK2)isassociatedwithvarioussystemicdiseases.However,littleisknownabouttheroleoftheCMPK2geneinsalivaanddyslipidemia.Thisstudyinvestigatedtherelationshipbetweenserumlipid[...]Readmore.Salivarybiomarkersarepromisingmoleculesfordinosingsystemicdiseases.Cytidine/uridinemonophosphatekinase2(CMPK2)isassociatedwithvarioussystemicdiseases.However,littleisknownabouttheroleoftheCMPK2geneinsalivaanddyslipidemia.ThisstudyinvestigatedtherelationshipbetweenserumlipidlevelsandCmpk2mRNAexpressioninthesalivaofdyslipidemicmice.Additionally,immunofluorescencestainingwasemployedtoassessthelocalizationoftheCMPK2proteininthesubmandibulargland.Twotypesofdyslipidemicmicewereutilized:micefedahigh-fatandhigh-cholesterol(HFHC)dietandgeneticallydyslipidemicApoE-deficientmice.Themiceat9to46weekswereanalyzedforserumlipidlevels,Cmpk2mRNAexpressioninsaliva,andCMPK2proteinlocalizationinthesubmandibularglands.Bothdyslipidemicmicedisplayedelevatedlow-densitylipoproteincholesterolandtotalcholesterolinserum.ApoE-deficientmiceapparentlyexhibitedincreasedCmpk2expressioninsaliva.ImmunofluorescencestainingindicatedthatCMPK2proteinswereprimarilylocalizedintheserousacini,potentiallyassociatedwiththesecretionofCmpk2mRNAinsaliva.ThesefindingssuggestthatCmpk2mRNAincreasesandisdetectableinthesalivaofdyslipidemicmice,providingaviableexperimentalmodeltoassessthepotentialuseofCMPK2asabiomarkerfordyslipidemia.Fullarticle(ThisarticlebelongstotheSpecialIssueRecentAdvancementsinBiomarkersforNoncommunicableDiseases)13pes,475KiB OpenAccessArticleEffectsofDifferentPlantingDensitiesofSolanumnigrumL.ontheGrowthandCadmiumUptakeofYoungGrapevinesbyYuanxiangYang,QinfengZheng,JinWang,XiulanLv,DongLiang,RenyanLiaoandLijinLinronomy2024,14(12),3056;doi.org/10.3390/ronomy(registering DOI)-21Dec2024AbstractAbstract:WedeterminethebestplantingdensityofSolanumnigrumL.whenintercroppingwithyounggrapevinestodecreasecadmium(Cd)uptakebyyounggrapevines.Theeffectsofdifferentplantingdensities(plantspacing×rowspacing,incentimeters,anddesignatedas40×80,[...]Readmore.Abstract:WedeterminethebestplantingdensityofSolanumnigrumL.whenintercroppingwithyounggrapevinestodecreasecadmium(Cd)uptakebyyounggrapevines.Theeffectsofdifferentplantingdensities(plantspacing×rowspacing,incentimeters,anddesignatedas40×80,40×40,20×40and20×20,respectively)ofS.nigrumonthegrowthandCduptakeofyounggrapevineswerestudied.The40×80and40×40treatmentsincreasedthebiomass,photosyntheticpigmentcontentandphotosynthesisofyounggrapevines,whilethe20×40and20×20treatmentsdecreasedthesetraitscomparedwiththemonoculture.Withincreasingintercroppingdensity,theantioxidantenzymeactivityofbothplantspeciesincreased.IntercroppingwithS.nigrumdecreasedtheCdcontentinyounggrapevines,andthe40×80,40×40,20×40and20×20treatmentsdecreasedtheshootCdcontentinyounggrapevinesby20.89%,26.11%,38.12%and45.95%,respectively,comparedwiththemonoculture.Additionally,increasingtheintercroppingdensityincreasedtheCdcontentandextractionofS.nigrum.Thus,intercroppingyounggrapevinewithS.nigrumcandecreaseCduptakeinyounggrapevineswhileremediatingsoilCd-contamination,andthemostoptimaltreatmentis20×20inthisexperiment.Fullarticle(ThisarticlebelongstotheSectionInnovativeCroppingSystems)83pes,KiB OpenAccessReviewAReviewofLargeLangueModels:FundamentalArchitectures,KeyTechnologicalEvolutions,InterdisciplinaryTechnologiesIntegration,OptimizationandCompressionTechniques,Applications,andChallengesbySongyueHan,MingyuWang,JialongZhang,DongdongLiandJunhongDuanElectronics2024,13(24),5040;doi.org/10.3390/electronics(registering DOI)-21Dec2024AbstractLargelanguemodel-relatedtechnologiesheshownastonishingpotentialintaskssuchasmachinetranslation,textgeneration,logicalreasoning,taskplanning,andmultimodalalignment.Consequently,theirapplicationshecontinuouslyexpandedfromnaturallangueprocessingtocomputervision,scientificcomputing,andotherverticalindustryfields.[...]Readmore.Largelanguemodel-relatedtechnologiesheshownastonishingpotentialintaskssuchasmachinetranslation,textgeneration,logicalreasoning,taskplanning,andmultimodalalignment.Consequently,theirapplicationshecontinuouslyexpandedfromnaturallangueprocessingtocomputervision,scientificcomputing,andotherverticalindustryfields.Thisrapidsurgeinresearchworkinashortperiodposessignificantchallengesforresearcherstocomprehensivelygrasptheresearchdynamics,understandkeytechnologies,anddevelopapplicationsinthefield.Toaddressthis,thispaperprovidesacomprehensivereviewofresearchonlargelanguemodels.First,itorganizesandreviewstheresearchbackgroundandcurrentstatus,clarifyingthedefinitionoflargelanguemodelsinbothChineseandEnglishcommunities.Second,itanalyzesthemainstreaminfrastructureoflargelanguemodelsandbrieflyintroducesthekeytechnologiesandoptimizationmethodsthatsupportthem.Then,itconductsadetailedreviewoftheintersectionsbetweenlargelanguemodelsandinterdisciplinarytechnologiessuchascontrastivelearning,knowledgeenhancement,retrievalenhancement,hallucinationdissolution,recommendationsystems,reinforcementlearning,multimodallargemodels,andents,pointingoutvaluableresearchideas.Finally,itorganizesthedeploymentandindustryapplicationsoflargelanguemodels,identifiesthelimitationsandchallengestheyface,andprovidesanoutlookonfutureresearchdirections.Ourreviewpaperaimsnotonlytoprovidesystematicresearchbutalsotofocusontheintegrationoflargelanguemodelswithinterdisciplinarytechnologies,hopingtoprovideideasandinspirationforresearcherstocarryoutindustryapplicationsandthesecondarydevelopmentoflargelanguemodels.Fullarticle(ThisarticlebelongstotheSpecialIssueRecentAdvancesinLargeLangueModels)9658;9660;ShowFiguresFigure1Figure2---Figure3---Figure4---Figure5---Figure6---Figure7---Figure8---Figure9---Figure10---Figure11---Figure12---Figure13---Figure14---Figure15---Figure16---Figure17---Figure18---Figure19---Figure20---Figure21---Figure22---Figure23---Figure24---Figure25---Figure26---Figure27---Figure28---Figure29---Figure30---Figure31---Figure32---Figure33---Figure34---Figure35---Figure36attachmentSupplementarymaterial:SupplementaryFile1(ZIP,459KiB)16pes,2393KiB OpenAccessArticleFullyAutomatedAssessmentofCardiacChamberVolumesandMyocardialMassonNon-ContrastChestCTwithaDeepLearningModel:ValidationainstCardiacMRbyRamonaSchmitt,ChristopherL.Schlett,JonathanI.Sperl,SaikiranRapaka,AthiraJ.Jacob,ManuelHein,MuhammadTahaHar,PhilippRuile,DirkWestermann,MartinSoschynski,FabianBambergandChristopherSchuppertDinostics2024,14(24),2884;doi.org/10.3390/dinostics(registering DOI)-21Dec2024AbstractBackground:Tovalidatetheautomatedquantificationofcardiacchambervolumesandmyocardialmassonnon-contrastchestCTusingcardiacMR(CMR)asareference.Methods:Weretrospectivelyincluded53consecutivepatientswhoreceivednon-contrastchestCTandCMRwithinthreeweeks.Adeep[...]Readmore.Background:Tovalidatetheautomatedquantificationofcardiacchambervolumesandmyocardialmassonnon-contrastchestCTusingcardiacMR(CMR)asareference.Methods:Weretrospectivelyincluded53consecutivepatientswhoreceivednon-contrastchestCTandCMRwithinthreeweeks.Adeeplearningmodelcreatedcardiacsegmentationsonaxialsoft-tissuereconstructionsfromCT,coveringallfourcardiacchambersandtheleftventricularmyocardium.SegmentationsonCMRcineshort-axisandlong-axisimesservedasareference.Standardestimatesofdinosticaccuracywerecalculatedforventricularvolumesatend-diastoleandend-systole(LVEDV,LVESV,RVEDV,RVESV),leftventricularmass(LVM),andatrialvolumes(LA,RA)atventricularend-diastole.Aqualitativeassessmentnotedsegmentationissues.Results:ThedeeplearningmodelgeneratedCTmeasurementsfor52ofthe53patients(98%).BasedonCMRmeasurements,theereLVEDVwas166±64mL,RVEDVwas144±51mL,andLVMwas115±39g.TheCTmeasurementscorrelatedwellwithCMRmeasurementsforLVEDV,LVESV,andLVM(r=0.85,r=0.84,andr=0.91;allp<0.001)andRVEDVandRVESV(r=0.82andr=0.84;bothp<0.001),andmoderatelywellwithLAandRA(r=0.77andr=0.67;bothp<0.001).AbsolutereementslikewiseforedLVEDV,LVESV,andLVM.ECG-gatingdidnotrelevantlyinfluencetheresults.TheCTresultscorrectlyidentified7/15LVand1/1RVasdilated(oneandsixfalsepositives,respectively).Majorqualitativeissueswerefoundinthreecases(6%).Conclusions:Automatedcardiacchambervolumeandmyocardialmassquantificationonnon-contrastchestCTproducedviablemeasurementsinthisretrospectivesample.RelevanceStatement:Anautomatedcardiacassessmentonnon-contrastchestCTprovidesquantitativemorphologicaldataontheheart,enablingapreliminaryorganevaluationthataidsinincidentallyidentifyingat-riskpatientswhomaybenefitfromamoretargeteddinosticworkup.Fullarticle(ThisarticlebelongstotheSpecialIssueCardiothoracicIming:DinosticsandModernTechniques—2ndEdition)23pes,1204KiB OpenAccessArticleRiverbedAdjustmentsinGrel–SandReachesImmediatelyDownstreamofLargeReservoirsbySixuanLi,LinglingZhu,JingYuan,BingjiangDong,ChaonanLvandChenggangYangSustainability2024,16(24),;doi.org/10.3390/su5(registering DOI)-21Dec2024AbstractTheoperationoflargereservoirssignificantlymodifiesflow–sedimentregimes,andthereachesimmediatelydownstreamofthedamsarethefirsttoundergoresponsivechanneladjustments.Consideringthatthegeomorphologicalresponsesaredirectlyrelatedtothefloodcontrolsafety,channelstabilityandothersustainable[...]Readmore.Theoperationoflargereservoirssignificantlymodifiesflow–sedimentregimes,andthereachesimmediatelydownstreamofthedamsarethefirsttoundergoresponsivechanneladjustments.Consideringthatthegeomorphologicalresponsesaredirectlyrelatedtothefloodcontrolsafety,channelstabilityandothersustainablefunctionsofrivers,thispaperexploresthesimilaritiesanddissimilaritiesofthechanneladjustmentsinthetworeacheswithgrel–sandbedsimmediatelydownstreamoftheXiangjiabareservoirandtheThreeGorgesDam,respectively.Theresultsshowthatmajorerosionprimarilyoccurredduringtheinitialyearsofreservoirimpoundment.Andthenwiththeprominentreductioninwashablesedimentontheriverbed,theerosionintensityfurtherweakened.Ittakes6to13yearsforthetworeachestoreachanewstateofrelativeequilibrium.Incomparison,aftertheequilibriumstatehasbeenachieved,thereachwithsignificanttributarysedimentinflowsexhibitsalternatingerosionanddepositiondynamics,whiletheotherremainsrelativelystable.ThetributariesthattransportalargeamountofsedimentduringfloodsarethemainsourcesofsedimentdepositioninthedownstreamreachesoftheXiangjiabareservoir.However,thetributaryinflowoftheQingRiverwithlowsedimentconcentrationshaslittleimpactontheriverbedevolutionofthereachesfromYichangtoZhichengimmediatelydownstreamoftheThreeGorgesDam.Thesefindingscontributetoadeeperunderstandingofgeomorphicadjustmentsneardamsinresponsetoupstreamdamming.Fullarticle(ThisarticlebelongstotheSpecialIssueSedimentMovement,SustainableWaterConservancyandWaterTransport)17pes,2079KiB OpenAccessArticleOptimizingCryopreservationProtocolsforCoffearacemosaandCoffealiberica:ImpactofMoistureContentandPackingonSeedViabilitybyStefaniaVilasBoasCoelho,SttelaDellyzeteVeigaFrancodaRosa,LilianPadilha,JanainaGuarieiroRibeirodeAssis,AnaLuizadeOliveiraVilela,AnaMariaOliveiraFerreira,OliveiroGuerreiroFilhoandMasakoTomaBrhinironomy2024,14(12),3058;doi.org/10.3390/ronomy(registering DOI)-21Dec2024AbstractCryopreservationprotocolshenotyetbeendefinedforseedsofsomeCoffeaspeciesduetotheirhighsensitivitytodesiccationandtoultra-lowtemperatures,factorsthatleadtolowseedsurvivalratesafterwarming.ThisreducedrateoccurPer favore aspetta... Clouddichiaratosduetoseveralfactorsthat[...]Readmore.CryopreservationprotocolshenotyetbeendefinedforseedsofsomeCoffeaspeciesduetotheirhighsensitivitytodesiccationandtoultra-lowtemperatures,factorsthatleadtolowseedsurvivalratesafterwarming.Thisreducedrateoccursduetoseveralfactorsthatcompromisecellularintegrityduringthestepsoftheprocess.Inthisstudy,weevaluatedtheeffectofmoisturecontentandthetypesofpackingonthecryopreservationofCoffearacemosaandCoffealibericavardewevreiseeds.Forthatpurpose,seedsweredriedtomoisturecontentsof18,20,and25%(drybasis—db)forC.racemosaandtocontentsof20,25,30,and35%forC.liberica.Theseedswerethenpackedinmeshbs,Falcontubes,andtriple-laminatedaluminumfoilpouchesbeforebeingdirectlyimmersedinliquidnitrogen.Physiologicalandbiochemicalanalyseswereperformedontheseeds.Therewasinteractionbetweenmoisturecontentandthepackingoftheseedsofthespecies.Dryingtheseedstoa20%moisturecontentandpackingthemintriple-laminatedaluminumfoilpouchesprovidedthebestcryopreservationprotocolamongthosestudied,withsurvivalratesof79and8%forC.racemosaandC.liberica,respectively.Fullarticle(ThisarticlebelongstotheSectionroecologyInnovation:AchievingSystemResilience)20pes,319KiB OpenAccessArticleLyapunovInequalitiesforSystemsofTemperedFractionalDifferentialEquationswithMulti-PointCoupledBoundaryConditionsviaaFixPointApproachbyHailongMaandHongyuLiFractalFract.2024,8(12),754;doi.org/10.3390/fractalfract(registering DOI)-21Dec2024AbstractInthispaper,westudyasystemofnonlineartemperedfractionaldifferentialequationswithmulti-pointcoupledboundaryconditions.ByapplyingthepropertiesofGreen’sfunctionandtheoperatorandcombiningthemethodofmatrixanalysis,weobtainthecorrespondingLyapunovinequalitiesundertwo[...]Readmore.Inthispaper,westudyasystemofnonlineartemperedfractionaldifferentialequationswithmulti-pointcoupledboundaryconditions.ByapplyingthepropertiesofGreen’sfunctionandtheoperatorandcombiningthemethodofmatrixanalysis,weobtainthecorrespondingLyapunovinequalitiesundertwoBanachspaces.And,wehecomparedtwoLyapunovinequalitiesundercertainconditions.Anexampleisgiventoverifyourresults.Fullarticle(ThisarticlebelongstotheSpecialIssueNonlinearFractionalDifferentialEquationandFixed-PointTheory)27pes,865KiB OpenAccessArticleSensitivityAnalysisofFactorsInfluencingCoalPricesinChinabyJingyeLyu,ChongLi,WenwenZhouandJinsuoZhangMathematics2024,12(24),4019;doi.org/10.3390/math(registering DOI)-21Dec2024AbstractAscientificassessmentofthesensitivityoftheChinesecoalmarkethasbecomeanimportantresearchtopic.ThispapercombinesGaussianProcessRegression(GPR)andSobolsensitivityanalysistoconstructaGPR–SobolhybridmodelinnovativelyappliedtotheChinesecoalmarket,thusaddressing[...]Readmore.AscientificassessmentofthesensitivityoftheChinesecoalmarkethasbecomeanimportantresearchtopic.ThispapercombinesGaussianProcessRegression(GPR)andSobolsensitivityanalysistoconstructaGPR–SobolhybridmodelinnovativelyappliedtotheChinesecoalmarket,thusaddressingagapintheeconomicapplicationsofthismethod.ThemodelisusedtoanalyzethesensitivityoffactorsinfluencingcoalpricesinChina.TheGPR–Sobolmodeleffectivelyhandlesnonlinearrelationships,enablinganin-depthexplorationofkeyfactorsaffectingpricevolatilityandquantifyingtheirimpacts,thusovercomingthelimitationsoftraditionaleconometricmodelsinnonlineardataprocessing.Theresultsindicatethateconomicgrowth,energyprices,interestrates,exchangerates,anduncertaintyfactorsexhibithighsensitivityandsignificantlyimpactcoalpricefluctuationsinChina.CoalpricesinnorthwestChinaaremoresensitivetointerestratesandgeopoliticalrisks,whilepricesineastandsouthChinaaremoreresponsivetoexchangeratesbutlesssotoeconomicpolicyuncertainty.Additionally,coalpricesinnorth,south,andeastChinaarehighlysensitivetointernationalenergyprices,indicatingthatcoalpricesaredominatedbytheglobalenergymarket,yettheirweakresponsetomacroeconomicindicatorssuggeststheseregionsisstillinsufficientlymature.Fullarticle15pes,KiB OpenAccessArticleFlow-InducedFatigueDameofLPer favore aspetta... ClouddichiaratoargeFrancisTurbinesUnderMultipleOperatingLoadsbyPinghuLiu,XingxingHuang,TianyuYangandZhengweiWangAppl.Sci.2024,14(24),;doi.org/10.3390/app3(registering DOI)-21Dec2024AbstractTheFrancisrunnerisacriticalcomponentoftheFrancisturbinegeneratorunit,playingacentralroleinconvertingwaterenergyintorotatingmechanicalenergythatdrivesthegeneratorinhydropowerstations.In-depthanalysesoftheflowcharacteristicsoftheFrancisrunnerunder[...]Readmore.TheFrancisrunnerisacriticalcomponentoftheFrancisturbinegeneratorunit,playingacentralroleinconvertingwaterenergyintorotatingmechanicalenergythatdrivesthegeneratorinhydropowerstations.In-depthanalysesoftheflowcharacteristicsoftheFrancisrunnerundervariousoperatingconditionsandoidingfatiguedameoftheFrancisrunnerarecrucialtothereliabilityandefficiencyofhydropoweroperation.Inthispaper,theflowdynamicsofalargeFrancisturbinerunnerareanalyzedunderthreerepresentativeloadingconditions—lowpartialload,highpartialload,andfullload—andtheflow-inducedstressoftherunnerisanalyzedundertheseloadingconditions.Itwasfoundthatthemaximumstaticanddynamicsstressesoftherunneratthreerepresentativeloadingconditionsarelocatedatthechamferedsurfacewherethebladetrailingedgeconnectstotherunnercrown.ThemaximumstaticstressesoftheFrancisrunnerare284MPa,352MPa,and381MPaatlowpartialload,highpartialload,andfullload,respectively,andtheyareabovetheallowablestresslimits,ashalfoftheyieldstressoftherunnermaterialof550MPa.Thepeak-to-peakvaluesofrunnerdynamicstressatlowpartialload,highpartialload,andfullloadare15MPa,25MPa,and14.6MPa,respectively.Thehighstressinvokedbytheunsteadyflowundervariousloadingconditionsinthisrunnerwasthecauseofthefatiguebreakeoftherunnerblades.TheresultsofthisinvestigationheimportantreferencevaluesformitigatingfatiguedameinsimilarFrancisrunnersandoptimizingunitoperation.Fullarticle(ThisarticlebelongstotheSpecialIssueAdvancedTechnologiesinRotatingMachinery:Design,Modeling,Manufacturing,Testing,andOperation)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,8003KiB)15pes,6121KiB OpenAccessArticleNetworkToxicologyandMolecularDockingAnalysisofTetracycline-InducedAcutePancreatitis:UnveilingCoreMechanismsandTargetsbyHangLei,YimaoWu,WenjunMa,JiaqiYao,PengchengZhang,YongTian,YuhongJiang,ZhijunXie,LvZhuandWenfuTangToxics2024,12(12),929;doi.org/10.3390/toxics(registering DOI)-21Dec2024AbstractAcutepancreatitis(AP),inducedbytetracycline,awidelyusedantibiotic,posessignificantclinicalandtoxicologicalchallenges,yetitsmolecularmechanismsremainunclear.Thisstudyaimstopromotedrugtoxicologystrategiesfortheeffectiveinvestigationoftheputativetoxicityandpotentialmolecularmechanismsof[...]Readmore.Acutepancreatitis(AP),inducedbytetracycline,awidelyusedantibiotic,posessignificantclinicalandtoxicologicalchallenges,yetitsmolecularmechanismsremainunclear.ThisstudyaimstopromotedrugtoxicologystrategiesfortheeffectiveinvestigationoftheputativetoxicityandpotentialmolecularmechanismsofantibioticdrugsthroughthestudyoftetracyclineinAP.UsingtheSwissTargetPrediction,SEASearch,Super-PRED,GeneCards,Drugbank,OnlineMendelianInheritanceinMan(OMIM),andTherapeuticTargetDatabase(TTD),weidentified259potentialtargetsassociatedwithtetracyclineexposureandAP.FurtherrefinementviatheSTRINGdatabaseandCytoscape(version3.10.1)softwarehighlighted22coretargets,includingTP53,TNF,andAKT1.FunctionalenrichmentviatheDatabaseforAnnotation,Visualization,andIntegratedDiscovery(DID)identifiedpathwaysthroughGeneOntology(GO)termsandtheKyotoEncyclopediaofGenesandGenomes(KEGG)database,highlightingPI3K-Akt,MAPK,HIF-1,andE-REascriticalmediatorsintetracycline-inducedAP.Moleculardockingconfirmedthestrongbindingbetweentetracyclineandthecoretargets.Overall,thesefindingssuggestthattetracyclinemayaffecttheoccurrenceandprogressionofpancreas-relatedinflammationbyregulatingpancreaticcellapoptosisandproliferation,activatinginflammatorysignalingpathways,andregulatinglipidmetabolicpathways.Thisstudyprovidesatheoreticalbasisforunderstandingthemolecularmechanismoftetracycline-inducedAPandlaysthefoundationforthepreventionandtreatmentofdigestivesystemdiseasesassociatedwithexcessiveexposuretotetracyclineantibioticsandcertaintetracyclines.Inaddition,ournetworktoxicologyapproachhasacceleratedtheelucidationoftoxicpathwaysinantibioticdrugsthatlackspecificcharacteristics.Fullarticle(ThisarticlebelongstotheSpecialIssueState-of-the-ArtEnvironmentalChemicalExposomicsandMetabolomics—2ndEdition)9658;9660;ShowFiguresFigure1Figure2---Figure3---Figure4---Figure5---Figure5Cont.---Figure6---Figure7---Figure7Cont.19pes,1643KiB OpenAccessArticleAnalysisofSelectedITToolsforEnvironmentalProductAssessmentbyDamianGrajewski,AnnaDudkowiak,MiłoszWiśniewskiandEwaDostatniAppl.Sci.2024,14(24),;doi.org/10.3390/app2(registering DOI)-21Dec2024AbstractThisarticlediscussesthesubjectoftheenvironmentalassessmentofproductsbasedonspecificmethods(LCA,ReCiPe,andSM2013)andtools(GaBi,SimaPro,andSustainableMinds).TheaimofthisworkwastoanalyzeselectedITtoolsforsupportingsuchanassessment.Assumptions[...]Readmore.Thisarticlediscussesthesubjectoftheenvironmentalassessmentofproductsbasedonspecificmethods(LCA,ReCiPe,andSM2013)andtools(GaBi,SimaPro,andSustainableMinds).TheaimofthisworkwastoanalyzeselectedITtoolsforsupportingsuchanassessment.Assumptionsandcriteriawereadopted,basedonwhichspecificITtoolswereselectedforacomparativeanalysis.Then,anenvironmentalassessmentofreferenceproductswascarriedoutusingthreedifferentITtools.Thestructureoftheproductswaspreparedinsuchawaythatthepartsandsubassembliesmettwobasicrequirements.First,theyweremadeofconstructionmaterialsthataregenerallyailableandusedinindustry.Thesecondrequirementwasthatthetechnologiesformanufacturingthesepartsincludedasmanyfrequentlyusedtechnologicalprocessesaspossible.ThisallowedforacomparisonoftheresultsofestimatedenvironmentalassessmentsgeneratedbyselectedITtools.Asaresult,thestrengthsandweaknessesofeachoftheITtoolswereidentified.Fullarticle(ThisarticlebelongstotheSectionEnvironmentalSciences)23pes,KiB OpenAccessArticleDynamicsModelandItsVerificationofAerospaceThree-RingGearReducerbyJinyongLai,LanLuo,GuangzhaoLuoandShiyuanChaoAerospace2024,11(12),1049;doi.org/10.3390/aerospace(registering DOI)-21Dec2024AbstractThispaperproposesanonlineardynamicmodelingmethodbasedonthelumpedmassapproachtoaddressthechallengeofmodelingthevibrationsoftheoutputexternalgearandinternalgearplateinanaerospacethree-ringgearreducer.Avibrationmodelofbending–torsioncoupling[...]Readmore.Thispaperproposesanonlineardynamicmodelingmethodbasedonthelumpedmassapproachtoaddressthechallengeofmodelingthevibrationsoftheoutputexternalgearandinternalgearplateinanaerospacethree-ringgearreducer.Avibrationmodelofbending–torsioncouplingwith12degreesoffreedomwasestablishedbycomprehensivelyconsideringfactorssuchasthetime-varyingmeshingstiffness,geartransmissionerror,toothsideclearance,bearingsupportstiffness,anddamping.Finiteelementmodalanalysisandvibrationtestresultsverifiedthevibrationmodel’saccuracyandapplicability,indicatingthatthemodelisbothpreciseandvalid.Thevibrationmodelwassolvedusingthefourth-order,five-levelRunge–Kuttamethod.Theresultsshowthatthesymmetricalarrangementdesignoftheinternalgearplatecancelsthevibrationsinalldirectionsandsuppressesthevibrationdisplacementresponseontheoutputshaft.Fullarticle(ThisarticlebelongstotheSectionAeronautics)9658;9660;ShowFiguresFigure1Figure2---Figure3---Figure4---Figure5---Figure6---Figure6Cont.---Figure7---Figure8---Figure9---Figure10---Figure11---Figure11Cont.---Figure12---Figure12Cont.---Figure13---Figure14---Figure15---Figure16---Figure1731pes,1334KiB OpenAccessArticleEmpoweringNanostoresforCompetitivenessandSustainableCommunitiesinEmergingCountries:AGenerativeArtificialIntelligenceStrategyIdeationProcessbyDidErnestoSalinas-Narro,EliseoVilalta-PerdomoandRosarioMichel-VillarrealSustainability2024,16(24),;doi.org/10.3390/su4(registering DOI)-21Dec2024AbstractThisexploratorystudyinvestigatesGenerativeArtificialIntelligence’s(GenAI)useinstrategyideationfornanostores—i.e.,smallindependentgroceryretailers—toenhancetheircompetitivenesswhilecontributingtocommunitysustainability.Nanostores,particularlyinemergingcountries,faceintensecompetitionandrapidlychangingtrends.Thesestoresadoptvariousstrategies[...]Readmore.ThisexploratorystudyinvestigatesGenerativeArtificialIntelligence’s(GenAI)useinstrategyideationfornanostores—i.e.,smallindependentgroceryretailers—toenhancetheircompetitivenesswhilecontributingtocommunitysustainability.Nanostores,particularlyinemergingcountries,faceintensecompetitionandrapidlychangingtrends.Thesestoresadoptvariousstrategiesbyleveringtheirproximitytoconsumersinneighbourhoods,resultingindifferentbusinessconfigurations.Whiletheexistingliteraturehighlightsthebroadernanostores’functions,thereislimitedresearchonhowtheymaydevelopcomprehensivestrategiestofacetheirchallenges.Byemployingathingethnographymethodology,thisworkproposesGenAIthinginterviewing—i.e.,withChatGPT3.5andMicrosoftCopilot—throughincrementalpromptingtoexplorepotentialstrategyideationandpractices.KeyfindingssuggestGenAIconversationscanaidshopkeepersinstrategyideationthroughhuman-likewrittenlangue,aligningwithsmallbusinessdynamicsandstructures.ThispropositionresultsinaGenAIideationframeworkforstrategygenerationanddefinition.Moreover,thistechnologycanenhancenanostorecompetitivenessandsustainabilityimpactbyenactingimprovedstrategypracticesinstakeholderengements.Accordingly,thiswork’smaincontributionunderscoresaGenAI-enabledconversationalapproachtofacilitatenanostores’strategyideationandembeddingineverydaybusinessoperations.FutureworkmustaddressthelimitationsandfurtherinvestigateGenAI’sinfluenceonhumanunderstandingandtechnologicalcreation,strategyideation,adoption,andusabilityinnanostores.Fullarticle(ThisarticlebelongstotheSpecialIssueSmallandMediumEnterprises:GreenOrientationsandSustainableBusinessModels)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,982KiB)19pes,6777KiB OpenAccessArticleCurcuminandMetforminInfiniteCoordinationPolymerNanoparticlesforCombinedTherapyofDiabeticMiceviaIntraperitonealInjectionsbySiweiSun,XinyiHou,KeLi,ChenqiHuang,YuRong,JiaoBi,XuepingLiandDaochengWuJ.Funct.Biomater.2024,15(12),388;doi.org/10.3390/jfb(registering DOI)-21Dec2024AbstractMetformin(Met)isoneofthemostcommonlyprescribedfirst-linedrugsfordiabetestreatment.However,ithasseveralissues,includinglowbioailability,therapeuticplatform,andsideeffectsathighdoses.InordertoimprovethetherapeuticefficiencyofMet,thisstudyproposesa[...]Readmore.Metformin(Met)isoneofthemostcommonlyprescribedfirst-linedrugsfordiabetestreatment.However,ithasseveralissues,includinglowbioailability,therapeuticplatform,andsideeffectsathighdoses.InordertoimprovethetherapeuticefficiencyofMet,thisstudyproposesastrategyofusingMetandcurcumin(Cur)toprepareCur-Zn(II)-Metinfinitecoordinationpolymernanoparticles(CMICPNPs),andcombiningthiswithintraperitonealinjections,forthetreatmentofdiabeticmice.Fouriertransforminfrared(FTIR)spectroscopy,X-rayphotoelectronspectroscopy(XPS),transmissionelectronmicroscopy(TEM),nanoparticleanalysis,cytotoxicityexperiments,andmiceexperimentswereusedtoinvestigatestructure,properties,andapplicationeffects.TheresultsshowedthatCMICPNPsexhibitahighdrugencapsulationrate(100%),goodstability,andanabsenceofinvivoandinvitrotoxicity.Thebloodglucoselevelofdiabeticmiceaftertreatmentwasreducedto6.7±0.65mmol/Lattheseventhweek.Intermsoftherapeuticmechanism,itappearsthatMetandCurcansynergisticallyregulatebloodglucoseinmicefrommultiplepaths.ThisstudyprovidesapromisingmethodforthetreatmentofdiabetesusingMetandotherdrugs.Fullarticle(ThisarticlebelongstotheSpecialIssueStateoftheArtinBiomaterialsforDrugDelivery)14pes,306KiB OpenAccessArticleNutritionalStatusofVeryElderlyOutpatientswithHeartFailureandItsInfluenceonPrognosisbySoniaGonzález-Sosa,PabloSantana-Vega,AlbaRodríguez-Quintana,JoseA.Rodríguez-González,JoséM.García-Vallejo,AliciaPuente-FernándezandAliciaConde-MartelNutrients2024,16(24),4401;doi.org/10.3390/nu(registering DOI)-21Dec2024AbstractAbstracts:Background/Objectives:Malnutritionhasbeenassociatedwithincreasedmorbidityandmortalityinelderlypatientsdinosedwithheartfailure(HF)[...]Fullarticle(ThisarticlebelongstotheSectionClinicalNutrition)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,1326KiB)13pes,2168KiB OpenAccessArticleCarrot-DerivedRhamnogalacturonan-IConsistentlyIncreasestheMicrobialProductionofHealth-PromotingIndole-3-PropionicAcidExVivobyAnnickMercenier,LamDaiVu,JonasPoppe,RuudAlbers,SueMcKayandPieterVandenAbbeeleMetabolites2024,14(12),722;doi.org/10.3390/metabo(registering DOI)-21Dec2024AbstractBackground:Usingdietaryinterventionstosteerthemetabolicoutputofthegutmicrobiotatowardsspecifichealth-promotingmetabolitesisoftenchallengingduetointerpersonalvariationintreatmentresponses.Methods:Inthisstudy,wecombinedtheexvivoSIFR®(SystemicIntestinalFermentationResearch)technology[...]Readmore.Background:Usingdietaryinterventionstosteerthemetabolicoutputofthegutmicrobiotatowardsspecifichealth-promotingmetabolitesisoftenchallengingduetointerpersonalvariationintreatmentresponses.Methods:Inthisstudy,wecombinedtheexvivoSIFR®(SystemicIntestinalFermentationResearch)technologywithuntargetedmetaboliteprofilingtoinvestigatetheimpactofcarrot-derivedrhamnogalacturonan-I(cRG-I)onexvivometaboliteproductionbythegutmicrobiotaof24humanadults.Results:Thefindingsrevealthatatadoseequivalentto1.5g/d,cRG-Iconsistentlypromotedindole-3-propionicacid(IPA)production(+45.8%increase)acrossallsubjects.Atadoseequivalentto0.3g/d,increasedIPAproductionwasalsoobserved(+14.6%),whichwascomparabletotheeffectseenfor1.5g/dinulin(10.6%).IPAhasbeenshowntoprovideprotectionainstdiseasesaffectingthegutandmultipleorgans.ThePearsoncorrelationanalysisrevealedastrongcorrelation(R=0.65,padjusted=6.1×10−16)betweentheincreasesinIPAlevelsandtheabsolutelevelsofBifidobacteriumlongum,aproducerofindole-3-lacticacid(ILA),anintermediateinIPAproduction.Finally,thecommunitymodulationscore,anoveldiversityindex,demonstratedthatcRG-Imaintainedahighα-diversitywhichhaspreviouslybeenlinkedtoelevatedIPAproduction.Conclusions:TheresultsfromtheexvivoSIFR®experimentmirroredclinicaloutcomesandprovidednovelinsightsintotheimpactofcRG-Ionthegutmicrobiomefunction.Importantly,wedemonstratedthatcRG-IpromotestryptophanconversionintoIPAviagutmicrobiomemodulation,thusconferringbenefitsviaaminoacidderivedmetabolitesextendingbeyondthosepreviouslyreportedforshortchainfattyacids(SCFA)resultingfromcarbohydratefermentation.Fullarticle(ThisarticlebelongstotheSpecialIssueTheRolesofDiet,GutMicrobiomeandMicrobialMetabolomeinPrecisionNutrition)9658;9660;ShowFiguresFigure1Figure2---Figure3---Figure412pes,5990KiB OpenAccessArticleMechanismofAluminiumElectrochemicalOxidationandAluminaDepositionUsingaCarbonSphereElectrodebyShuminYang,AoWang,XuemeiLin,YunkaiQi,GuochaoShi,WeiHanandJianjunGuCrystals2024,14(12),1102;doi.org/10.3390/cryst(registering DOI)-21Dec2024AbstractUsingelectromneticandelectrochemicaltheoriesasaframework,thisstudyexaminestheinfluenceofcarbonsphereelectrodesonthedistributionpatternsofanodicoxidationanddepositioncurrentdensitiesinmetallicaluminiumandporousanodicalumina.Theoreticalcalculationsshowthatthecurrentdensitysymmetrically[...]Readmore.Usingelectromneticandelectrochemicaltheoriesasaframework,thisstudyexaminestheinfluenceofcarbonsphereelectrodesonthedistributionpatternsofanodicoxidationanddepositioncurrentdensitiesinmetallicaluminiumandporousanodicalumina.Theoreticalcalculationsshowthatthecurrentdensitysymmetricallydecreasesfromthecentreoutwardundertheeffectofcarbonsphereelectrodes.Increasingtheelectrodedistanceimprovestheuniformityofthecurrentdistributionacrossthefilm,whiledecreasingthedistanceincreasestherateofgradientchangeincurrentdensity.Simulationresultsrevealthatatelectrodespacingsof15cmand1cm,theoxidationcurrentdensityatthefilmcentreis1333A/m2and2.9×105A/m2,respectively.Thecurrentdensitygraduallydecreasesoutwardalongtheradius,reaching1330A/m2and1.8×105A/m2attheedges,withobservedcurrentdensitygradientchangeratesof500A/m3and1.83×107A/m3,respectively.Experimentalresultsconfirmthatcarbonspherecounterelectrodescancreatenon-uniformoxidationanddepositionelectricfields.Microstructureswithgraduallyvaryingsymmetrycanbegeneratedbyadjustingtheelectrodespacing,resultinginporousanodicaluminaandcompositefilmsexhibitingiridescent,ring-likestructuralcolours.Theexperimentalfindingsalignwellwiththeoreticalcalculationsandsimulationresults.Fullarticle(ThisarticlebelongstotheSectionMaterialsforEnergyApplications)9658;9660;ShowFiguresFigure1Figure2---Figure3---Figure4---Figure5---Figure6---Figure7---Figure8---Figure9---Figure10---Figure1121pes,KiB OpenAccessArticleReframing‘PrimitiveHuts’fromStructuraltoEnvironmentalTechniquesandTheirNewInterrelationshipintheMachineebyEun-JiCho,DolaanaKhovalygandSung-TaegNamBuildings2024,14(12),4072;doi.org/10.3390/buildings(registering DOI)-21Dec2024AbstractThisstudyexamines‘PrimitiveHuts’inrelationtothestructuralandenvironmentaltechniquesrefinedbysants(e.g.,architectsandscholars)duringtheMachineethroughthreetypesofinterrelationships:separation,moderation,andintegration.Thefirstaimistoreframethetheoriesof‘Primitive[...]Readmore.Thisstudyexamines‘PrimitiveHuts’inrelationtothestructuralandenvironmentaltechniquesrefinedbysants(e.g.,architectsandscholars)duringtheMachineethroughthreetypesofinterrelationships:separation,moderation,andintegration.Thefirstaimistoreframethetheoriesof‘PrimitiveHuts’,shiftingthefocusfromstructuraltoenvironmentaltechniquesacrosstwoeras—theprimitiveandtheMachinee.Returningtotheconceptof‘PrimitiveHuts’inthecontextoftheMachineeaimstorebuildoriginality.Inparticular,thisinvestigationlooksintohowthe‘PrimitiveHut’hassoughtwaystoaddressenvironmentalchallenges.ThesecondexploreshowtheMachineeinitiallyprovokedtheseparationof‘PrimitiveHuts’—structuralandenvironmentaltechniques—andintegration(i.e.,newinterrelationship)throughmoderation.Asaresult,thecontributionsofsantsareanalysedtohighlighttheenhancedprecision,discipline,andefficiencythatheevolvedsincetheIndustrialRevolution.Fullarticle14pes,1931KiB OpenAccessArticleMicro-CTAssessmentDuringEmbeddingofPrototypeTiAlloyMulti-SpikedConnectingScaffoldinSubchondralTrabecularBoneofOsteoarthriticFemoralHeads,DependingonHostBMIbyRyszardUklejewski,MariuszWiniecki,AdamPatalas,PatrykMietliński,PawełZawadzkiandMikołajDąbrowskiJ.Funct.Biomater.2024,15(12),387;doi.org/10.3390/jfb(registering DOI)-21Dec2024AbstractTheprototypeofabiomimeticmulti-spikedconnectingscaffold(MSC-Scaffold)representsanessentialinnovationinthefixationinsubchondraltrabecularboneofcomponentsforanewgenerationofentirelycementlesshipresurfacingarthroplasty(RA)endoprostheses.Indesigningsuchafunctionalbiomaterialscaffold,identifyingthe[...]Readmore.Theprototypeofabiomimeticmulti-spikedconnectingscaffold(MSC-Scaffold)representsanessentialinnovationinthefixationinsubchondraltrabecularboneofcomponentsforanewgenerationofentirelycementlesshipresurfacingarthroplasty(RA)endoprostheses.Indesigningsuchafunctionalbiomaterialscaffold,identifyingthemicrostructuralandmechanicalpropertiesofthehostbonecompromisedbydegenerativediseaseiscrucialforproperpost-operativefunctioningandlong-termmaintenanceoftheendoprosthesiscomponents.Thisstudyaimedtoexplore,dependingontheoccurrenceofobesity,changesinthemicrostructureandmechanicalpropertiesofthesubchondraltrabecularboneinfemoralheadsofosteoarthritis(OA)patientscausedbytheMSC-Scaffoldembedding.Computedmicrotomography(micro-CT)scanningoffemoralheadsfromOApatientswasconductedbeforeandafterthemechanicalembeddingoftheMSC-Scaffold.Bonemorphometricparameterssuchasbonevolume/totalvolume(BV/TV),trabecularthickness(Tb.Th),andtrabecularnumber(Tb.N)forregionssurroundingtheMSC-Scaffoldwerecomputed,andthemechanicalpropertiessuchasbonedensity(ρB),bonecompressivestrength(S),andtheYoung’smodulus(E)withintheseregionswerecalculated.AstatisticallysignificantincreaseinBV/TV(by15.0%and24.9%)andTb.Th(by13.1%and42.5%)andadecreaseinTb.N(by15.2%and23.6%)wereobserved,whichtranslatestoanincreaseinρB(by15.0%and24.9%),S(by28.8%and49.5%),andE(by18.0%and29.8%)innon-obesepatientsandobesepatients,respectively.Thesechangesinpropertiesareforableforthemechanicalloads’transferfromtheartificialjointsurfaceviatheMSC-ScaffoldtotheperiarticulartrabecularboneoftheOAfemoralheadinthepostoperativeperiod.Fullarticle(ThisarticlebelongstotheSpecialIssueFunctionalScaffoldsforBoneandJointSurgery)9658;9660;ShowFiguresFigure1Figure2---Figure3---Figure436pes,3452KiB OpenAccessArticleASmartContract-BasedAlgorithmforOfflineUTaskCollaboration:ANewSolutionforManingCommunicationInterruptionsbyLinchaoZhang,LeiHang,KekeZuandYiWangDrones2024,8(12),781;doi.org/10.3390/drones(registering DOI)-21Dec2024AbstractEnvironmentalfactorsandelectronicinterferenceoftendisruptcommunicationbetweenUswarmsandgroundcontrolcenters,requiringUstocompletemissionsautonomouslyinofflineconditions.However,currentcoordinationschemesforUswarmsheilydependongroundcontrol,lackingrobustmechanismsforofflinetaskallocation[...]Readmore.EnvironmentalfactorsandelectronicinterferenceoftendisruptcommunicationbetweenUswarmsandgroundcontrolcenters,requiringUstocompletemissionsautonomouslyinofflineconditions.However,currentcoordinationschemesforUswarmsheilydependongroundcontrol,lackingrobustmechanismsforofflinetaskallocationandcoordination,whichcompromisesefficiencyandsecurityindisconnectedsettings.Thislimitationisespeciallycriticalforcomplexmissions,suchasrescueorattackoperations,underscoringtheneedforasolutionthatensuresbothmissioncontinuityandcommunicationsecurity.Toaddressthesechallenges,thispaperproposesanofflinetask-coordinationalgorithmbasedonblockchainsmartcontracts.Thisalgorithmintegratestaskallocation,resourcescheduling,andcoordinationstrategiesdirectlyintosmartcontracts,allowingUswarmstoautonomouslymakedecisionsandcoordinatetaskswhileoffline.Experimentalsimulationsconfirmthattheproposedalgorithmeffectivelycoordinatestasksandmaintainscommunicationsecurityinofflinestates,significantlyenhancingtheswarm’sautonomousperformanceincomplex,dynamicscenarios.Fullarticle(ThisarticlebelongstotheSectionDroneCommunications)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,99KiB)23pes,386KiB OpenAccessArticleTheBeneficialDietaryEffectofDriedOlivePulponSomeNutritionalCharacteristicsofEggsProducedbyMid-andLate-LayingHensbyAnnaDedousi,CharalamposKotzamanidis,GeorgiaDimitropoulou,ThemistoklisSfetsas,AndigoniMalousi,VirginiaGiantziandEvangeliaSossidouFoods2024,13(24),4152;doi.org/10.3390/foods(registering DOI)-21Dec2024AbstractThisresearchevaluatedtheimpactofincorporatingdriedolivepulp(OP)intothefeedoflayinghensonthefattyacidprofile,cholesterol,triglyceride,totalphenolic,oleuropeinandhydroxytyrosolcontent,andhealthlipidindicesofeggsproducedbymid-(39weeks)andlate-laying[...]Readmore.Thisresearchevaluatedtheimpactofincorporatingdriedolivepulp(OP)intothefeedoflayinghensonthefattyacidprofile,cholesterol,triglyceride,totalphenolic,oleuropeinandhydroxytyrosolcontent,andhealthlipidindicesofeggsproducedbymid-(39weeks)andlate-laying(59weeks)birds.Overa36-weektrial,300eggsfrom180Isa-Brownhens,assignedtothreedietarygroupswithdifferentOPlevels(CON,OP4andOP6),wereanalyzed.OPreducedeggcholesterol,withsignificanteffectsinlate-eeggs(p<0.05).Inmid-ehens,theOP6eggshadhighertotalphenolicsthanthecontrols(p<0.05)andmorePUFAsthantheothergroups(p<0.05).Theconcentrationoftotalphenolics,cholesterol,n3PUFAsand%fatincreasedwithhene(p<0.05),whiletriglyceridesandoleuropeindecreased(p<0.05).Withincreasinghene,theSFAsintheOPeggsdecreased(p<0.05)andtheMUFAsincreased(p<0.05).Eggsfromolderhenshadhighernutritionalvalue,asindicatedbythelowern6/n3PUFAratio,lowerAIandTIindices,andhigherh/Hratio(p<0.05).Overall,dietaryOPsupplementationimprovedthenutritionalqualityofeggs,suggestingpotentialhealthbenefits.Ourresultsalsohighlightedeggsfromolderhensasavaluablesourceofhigh-qualityfats.Fullarticle(ThisarticlebelongstotheSpecialIssuero-FoodChainBy-ProductsandPlantOriginFoodstoObtainHigh-Value-AddedFoods—2ndEdition)MoreArticles...OpenAccessJournalsAcousticsActaMicrobiologicaHellenica(AMH)ActuatorsAdministrativeSciencesAdolescentsAdvancesinRespiratoryMedicine(ARM)AerobiologyAerospacericultureriEngineeringrochemicalsronomyAIAirAlgorithmsAllergiesAlloysAnalyticaAnalyticsAnatomiaAnesthesiaResearchAnimalsAntibioticsAntibodiesAntioxidantsAppliedBiosciencesAppliedMechanicsAppliedMicrobiologyAppliedNanoAppliedSciencesAppliedSystemInnovation(ASI)AppliedChemAppliedMathAquacultureJournalArchitectureArthropodaArtsAstronomyAtmosphereAtomsAudiologyResearchAutomationAxiomsBacteriaBatteriesBehioralSciencesBeveresBigDataandCognitiveComputing(BDCC)BioChemBioengineeringBiologicsBiologyBiologyandLifeSciencesForumBiomassBiomechanicsBioMedBiomedicinesBioMedInformaticsBiomimeticsBiomoleculesBiophysicaBiosensorsBioTechBirdsBlockchainsBrainSciencesBuildingsBusinessesCCancersCardiogeneticsCatalystsCellsCeramicsChallengesChemEngineeringChemistryChemistryProceedingsChemosensorsChildrenChipsCivilEngCleanTechnologies(CleanTechnol.)ClimateClinicalandTranslationalNeuroscience(CTN)ClinicalBioenergeticsClinicsandPracticeClocks&SleepCoastsCoatingsColloidsandInterfacesColorantsCommoditiesComplicationsCompoundsComputationComputerSciences&MathematicsForumComputersCondensedMatterConservationConstructionMaterialsCorrosionandMaterialsDegradation(CMD)CosmeticsCOVIDCropsCryoCryptographyCrystalsCurrentIssuesinMolecularBiology(CIMB)CurrentOncologyDairyDataDentistryJournalDermatoDermatopathologyDesignsDiabetologyDinosticsDieteticsDigitalDisabilitiesDiseasesDiversityDNADronesDrugsandDrugCandidates(DDC)DynamicsEarthEcologiesEconometricsEconomiesEducationSciencesElectricityElectrochemElectronicMaterialsElectronicsEmergencyCareandMedicineEncyclopediaEndocrinesEnergiesEnergyStoreandApplications(ESA)EngEngineeringProceedingsEntropyEnvironmentalandEarthSciencesProceedingsEnvironmentsEpidemiologiaEpigenomesEuropeanBurnJournal(EBJ)EuropeanJournalofInvestigationinHealth,PsychologyandEducation(EJIHPE)FermentationFibersFinTechFireFishesFluidsFoodsForecastingForensicSciencesForestsFossilStudiesFoundationsFractalandFractional(FractalFract)FuelsFutureFutureInternetFuturePharmacologyFutureTransportationGalaxiesGamesGasesGastroenterologyInsightsGastrointestinalDisordersGastronomyGelsGenealogyGenesGeographiesGeoHazardsGeomaticsGeometryGeosciencesGeotechnicsGeriatricsGlaciesGout,Urate,andCrystalDepositionDisease(GUCDD)GrassesHardwareHealthcareHeartsHematoHematologyReportsHeriteHistoriesHorticulturaeHospitalsHumanitiesHumansHydrobiologyHydrogenHydrologyHygieneImmunoInfectiousDiseaseReportsInformaticsInformationInfrastructuresInorganicsInsectsInstrumentsIntelligentInfrastructureandConstructionInternationalJournalofEnvironmentalResearchandPublicHealth(IJERPH)InternationalJournalofFinancialStudies(IJFS)InternationalJournalofMolecularSciences(IJMS)InternationalJournalofNeonatalScreening(IJNS)InternationalJournalofPlantBiology(IJPB)InternationalJournalofTopologyInternationalJournalofTranslationalMedicine(IJTM)InternationalJournalofTurbomachinery,PropulsionandPower(IJTPP)InternationalMedicalEducation(IME)InventionsIoTISPRSInternationalJournalofGeo-Information(IJGI)JJournalofeingandLongevity(JAL)JournalofCardiovascularDevelopmentandDisease(JCDD)JournalofClinical&TranslationalOphthalmology(JCTO)JournalofClinicalMedicine(JCM)JournalofCompositesScience(J.Compos.Sci.)JournalofCybersecurityandPrivacy(JCP)JournalofDementiaandAlzheimer039;sDisease(JDAD)JournalofDevelopmentalBiology(JDB)JournalofExperimentalandTheoreticalAnalyses(JETA)JournalofFunctionalBiomaterials(JFB)JournalofFunctionalMorphologyandKinesiology(JFMK)JournalofFungi(JoF)JournalofIming(J.Iming)JournalofIntelligence(J.Intell.)JournalofLowPowerElectronicsandApplications(JLPEA)JournalofManufacturingandMaterialsProcessing(JMMP)JournalofMarineScienceandEngineering(JMSE)JournalofMarketAccess&HealthPolicy(JMAHP)JournalofMolecularPathology(JMP)JournalofNanotheranostics(JNT)JournalofNuclearEngineering(JNE)JournalofOtorhinolaryngology,HearingandBalanceMedicine(JOHBM)JournalofParksJournalofPersonalizedMedicine(JPM)JournalofPharmaceuticalandBioTechIndustry(JPBI)JournalofRespiration(JoR)JournalofRiskandFinancialManement(JRFM)JournalofSensorandActuatorNetworks(JSAN)JournaloftheOmanMedicalAssociation(JOMA)JournalofTheoreticalandAppliedElectronicCommerceResearch(JTAER)JournalofVascularDiseases(JVD)JournalofXenobiotics(JoX)JournalofZoologicalandBotanicalGardens(JZBG)JournalismandMediaKidneyandDialysisKinasesandPhosphatasesKnowledgeLabMedLaboratoriesLandLanguesLawsLifeLimnologicalReviewLipidologyLiquidsLiteratureLiversLogicsLogisticsLubricantsLymphaticsMachineLearningandKnowledgeExtraction(MAKE)MachinesMacromolMnetismMnetochemistryMarineDrugsMaterialsMaterialsProceedingsMathematicalandComputationalApplications(MCA)MathematicsMedicalSciencesMedicalSciencesForumMedicinaMedicinesMembranesMeritsMetabolitesMetalsMeteorologyMethaneMethodsandProtocols(MPs)MetricsMetrologyMicroMicrobiologyResearchMicromachinesMicroorganismsMicroplasticsMineralsMiningModellingModernMathematicalPhysicsMolbankMoleculesMultimodalTechnologiesandInteraction(MTI)MusclesNanoenergyAdvancesNanomanufacturingNanomaterialsNDTNetworkNeurogliaNeurologyInternationalNeuroSciNitrogenNon-CodingRNA(ncRNA)NursingReportsNutraceuticalsNutrientsObesitiesOceansOncoOpticsOralOrganicsOrganoidsOsteologyOxygenParasitologiaParticlesPathogensPathophysiologyPediatricReportsPetsPharmaceuticalsPharmaceuticsPharmacoepidemiologyPharmacyPhilosophiesPhotochemPhotonicsPhycologyPhyschemPhysicalSciencesForumPhysicsPhysiologiaPlantsPlasmaPlatformsPollutantsPolymersPolysaccharidesPopulationsPoultryPowdersProceedingsProcessesProsthesisProteomesPsychiatryInternationalPsychoactivesPsychologyInternationalPublicationsQuantumBeamScience(QuBS)QuantumReportsQuaternaryRadiationReactionsRealEstateReceptorsRecyclingRegionalScienceandEnvironmentalEconomics(RSEE)ReligionsRemoteSensingReportsReproductiveMedicine(Reprod.Med.)ResourcesRheumatoRisksRoboticsRuminantsSafetySciScientiaPharmaceutica(Sci.Pharm.)SclerosisSeedsSensorsSeparationsSexesSignalsSinusitisSmartCitiesSocialSciencesSociétéInternationaled’UrologieJournal(SIUJ)SocietiesSoftwareSoilSystemsSolarSolidsSpectroscopyJournalSportsStandardsStatsStressesSurfacesSurgeriesSurgicalTechniquesDevelopmentSustainabilitySustainableChemistrySymmetrySynBioSystemsTargetsTaxonomyTechnologiesTelecomTextilesThalassemiaReportsTherapeuticsThermoTimeandSpaceTomographyTourismandHospitalityToxicsToxinsTransplantologyTraumaCareTrendsinHigherEducationTropicalMedicineandInfectiousDisease(TropicalMed)UniverseUrbanScienceUroVaccinesVehiclesVenereologyVeterinarySciencesVibrationVirtualWorldsVirusesVisionWasteWaterWildWindWomenWorldWorldElectricVehicleJournal(WEVJ)YouthZoonoticDiseases9658;9660;BrowsebyIndexingScopusWebofScienceSCIESSCIAHCIESCIPubMedMEDLINEPMCEmbaseEiCompendexInspecCAPlus/SciFinder9658;9660;BrowsebySubjectBiology&LifeSciencesBusiness&EconomicsChemistry&MaterialsScienceComputerScience&MathematicsEngineeringEnvironmental&EarthSciencesMedicine&PharmacologyPhysicalSciencesPublicHealth&HealthcareSocialSciences,ArtsandHumanities9658;9660;SelectedJournalsAppliedSciencesIMPACTFACTOR2.5IJMSIMPACTFACTOR4.9SustainabilityIMPACTFACTOR3.3JCMIMPACTFACTOR3.0SensorsIMPACTFACTOR3.4EnergiesIMPACTFACTOR3.0MaterialsIMPACTFACTOR3.1MoleculesIMPACTFACTOR4.2ElectronicsIMPACTFACTOR2.6RemoteSensingIMPACTFACTOR4.2NutrientsIMPACTFACTOR4.8FoodsIMPACTFACTOR4.7MathematicsIMPACTFACTOR2.3BuildingsIMPACTFACTOR3.1CancersIMPACTFACTOR4.5WaterIMPACTFACTOR3.0AnimalsIMPACTFACTOR2.7PlantsIMPACTFACTOR4.0PolymersIMPACTFACTOR4.7ronomyIMPACTFACTOR3.3ProcessesIMPACTFACTOR2.8DinosticsIMPACTFACTOR3.0LandIMPACTFACTOR3.2BiomedicinesIMPACTFACTOR3.9MicroorganismsIMPACTFACTOR4.1JMSEIMPACTFACTOR2.7ricultureIMPACTFACTOR3.3HealthcareIMPACTFACTOR2.4ForestsIMPACTFACTOR2.4MedicinaIMPACTFACTOR2.4CellsIMPACTFACTOR5.1NanomaterialsIMPACTFACTOR4.4LifeIMPACTFACTOR3.2PharmaceuticalsIMPACTFACTOR4.3SymmetryIMPACTFACTOR2.2IJERPHVirusesIMPACTFACTOR3.8BiomoleculesIMPACTFACTOR4.8AntioxidantsIMPACTFACTOR6.0BehioralSciencesIMPACTFACTOR2.5GenesIMPACTFACTOR2.8AtmosphereIMPACTFACTOR2.5ChildrenIMPACTFACTOR2.0ReligionsIMPACTFACTOR0.7PharmaceuticsIMPACTFACTOR4.9MetalsIMPACTFACTOR2.6CoatingsIMPACTFACTOR2.9EducationSciencesIMPACTFACTOR2.5MicromachinesIMPACTFACTOR3.0HorticulturaeIMPACTFACTOR3.1AntibioticsIMPACTFACTOR4.3BioengineeringIMPACTFACTOR3.8VaccinesIMPACTFACTOR5.2MineralsIMPACTFACTOR2.2BrainSciencesIMPACTFACTOR2.7BiologyIMPACTFACTOR3.6EntropyIMPACTFACTOR2.1PathogensIMPACTFACTOR3.3PhotonicsIMPACTFACTOR2.1CatalystsIMPACTFACTOR3.8MachinesIMPACTFACTOR2.1InsectsIMPACTFACTOR2.7ExploreAllJournals...HighlyAccessedArticlesLatestBooksMoreBooksandReprints...News17December2024Over100GermanUniversitiesPartnerwithMDPIinNewNationalreement17December2024ArticleLayoutandTemplateRevisedforFutureVolumes12December2024MDPISignsFlat-FeePublishingreementwithUniversidadCatólicaSanVicenteMártirdeValencia(UCV)MoreNews&Announcements...BlogPostsMoreFromOurBlog...TopicsMoreTopics...SelectedSpecialIssuesSelectedCollectionsFeedbackWearekeentohearwhatyouthinkaboutMDPI.Feedback,suggestions,questions?AboutMDPIMDPI.comisaplatformforpeer-reviewed,scientificopen-accessjournalsoperatedbyMDPI.ReadmoreaboutMDPIJournalsbySubjectBiology&LifeSciencesBusiness&EconomicsChemistry&MaterialsScienceComputerScience&MathematicsEngineeringEnvironmental&EarthSciencesMedicine&PharmacologyPhysicalSciencesPublicHealth&HealthcareSocialSciences,ArtsandHumanitiesBiology&LifeSciencesBusiness&EconomicsChemistry&MaterialsScienceComputerScience&MathematicsEngineeringEnvironmental&EarthSciencesMedicine&PharmacologyPhysicalSciencesPublicHealth&HealthcareSocialSciences,ArtsandHumanitiesFurtherInformationArticleProcessingChargesPayanInvoiceOpenAccessPolicyContactMDPIJobsatMDPIGuidelinesForAuthorsForReviewersForEditorsForLibrariansForPublishersForSocietiesForConferenceOrganizersMDPIInitiativesSciforumMDPIBooksPreprints.orgScilitSciProfilesEncyclopediaJAMSProceedingsSeriesFollowMDPILinkedInFacebookTwitterSubscribetoreceiveissuereleasenotificationsandnewslettersfromMDPIjournalsAcousticsActaMicrobiologicaHellenicaActuatorsAdministrativeSciencesAdolescentsAdvancesinRespiratoryMedicineAerobiologyAerospacericultureriEngineeringrochemicalsronomyAIAirAlgorithmsAllergiesAlloysAnalyticaAnalyticsAnatomiaAnesthesiaResearchAnimalsAntibioticsAntibodiesAntioxidantsAppliedBiosciencesAppliedMechanicsAppliedMicrobiologyAppliedNanoAppliedSciencesAppliedSystemInnovationAppliedChemAppliedMathAquacultureJournalArchitectureArthropodaArtsAstronomyAtmosphereAtomsAudiologyResearchAutomationAxiomsBacteriaBatteriesBehioralSciencesBeveresBigDataandCognitiveComputingBioChemBioengineeringBiologicsBiologyBiologyandLifeSciencesForumBiomassBiomechanicsBioMedBiomedicinesBioMedInformaticsBiomimeticsBiomoleculesBiophysicaBiosensorsBioTechBirdsBlockchainsBrainSciencesBuildingsBusinessesCCancersCardiogeneticsCatalystsCellsCeramicsChallengesChemEngineeringChemistryChemistryProceedingsChemosensorsChildrenChipsCivilEngCleanTechnologiesClimateClinicalandTranslationalNeuroscienceClinicalBioenergeticsClinicsandPracticeClocks&SleepCoastsCoatingsColloidsandInterfacesColorantsCommoditiesComplicationsCompoundsComputationComputerSciences&MathematicsForumComputersCondensedMatterConservationConstructionMaterialsCorrosionandMaterialsDegradationCosmeticsCOVIDCropsCryoCryptographyCrystalsCurrentIssuesinMolecularBiologyCurrentOncologyDairyDataDentistryJournalDermatoDermatopathologyDesignsDiabetologyDinosticsDieteticsDigitalDisabilitiesDiseasesDiversityDNADronesDrugsandDrugCandidatesDynamicsEarthEcologiesEconometricsEconomiesEducationSciencesElectricityElectrochemElectronicMaterialsElectronicsEmergencyCareandMedicineEncyclopediaEndocrinesEnergiesEnergyStoreandApplicationsEngEngineeringProceedingsEntropyEnvironmentalandEarthSciencesProceedingsEnvironmentsEpidemiologiaEpigenomesEuropeanBurnJournalEuropeanJournalofInvestigationinHealth,PsychologyandEducationFermentationFibersFinTechFireFishesFluidsFoodsForecastingForensicSciencesForestsFossilStudiesFoundationsFractalandFractionalFuelsFutureFutureInternetFuturePharmacologyFutureTransportationGalaxiesGamesGasesGastroenterologyInsightsGastrointestinalDisordersGastronomyGelsGenealogyGenesGeographiesGeoHazardsGeomaticsGeometryGeosciencesGeotechnicsGeriatricsGlaciesGout,Urate,andCrystalDepositionDiseaseGrassesHardwareHealthcareHeartsHematoHematologyReportsHeriteHistoriesHorticulturaeHospitalsHumanitiesHumansHydrobiologyHydrogenHydrologyHygieneImmunoInfectiousDiseaseReportsInformaticsInformationInfrastructuresInorganicsInsectsInstrumentsIntelligentInfrastructureandConstructionInternationalJournalofEnvironmentalResearchandPublicHealthInternationalJournalofFinancialStudiesInternationalJournalofMolecularSciencesInternationalJournalofNeonatalScreeningInternationalJournalofPlantBiologyInternationalJournalofTopologyInternationalJournalofTranslationalMedicineInternationalJournalofTurbomachinery,PropulsionandPowerInternationalMedicalEducationInventionsIoTISPRSInternationalJournalofGeo-InformationJJournalofeingandLongevityJournalofCardiovascularDevelopmentandDiseaseJournalofClinical&TranslationalOphthalmologyJournalofClinicalMedicineJournalofCompositesScienceJournalofCybersecurityandPrivacyJournalofDementiaandAlzheimer039;sDiseaseJournalofDevelopmentalBiologyJournalofExperimentalandTheoreticalAnalysesJournalofFunctionalBiomaterialsJournalofFunctionalMorphologyandKinesiologyJournalofFungiJournalofImingJournalofIntelligenceJournalofLowPowerElectronicsandApplicationsJournalofManufacturingandMaterialsProcessingJournalofMarineScienceandEngineeringJournalofMarketAccess&HealthPolicyJournalofMolecularPathologyJournalofNanotheranosticsJournalofNuclearEngineeringJournalofOtorhinolaryngology,HearingandBalanceMedicineJournalofParksJournalofPersonalizedMedicineJournalofPharmaceuticalandBioTechIndustryJournalofRespirationJournalofRiskandFinancialManementJournalofSensorandActuatorNetworksJournaloftheOmanMedicalAssociationJournalofTheoreticalandAppliedElectronicCommerceResearchJournalofVascularDiseasesJournalofXenobioticsJournalofZoologicalandBotanicalGardensJournalismandMediaKidneyandDialysisKinasesandPhosphatasesKnowledgeLabMedLaboratoriesLandLanguesLawsLifeLimnologicalReviewLipidologyLiquidsLiteratureLiversLogicsLogisticsLubricantsLymphaticsMachineLearningandKnowledgeExtractionMachinesMacromolMnetismMnetochemistryMarineDrugsMaterialsMaterialsProceedingsMathematicalandComputationalApplicationsMathematicsMedicalSciencesMedicalSciencesForumMedicinaMedicinesMembranesMeritsMetabolitesMetalsMeteorologyMethaneMethodsandProtocolsMetricsMetrologyMicroMicrobiologyResearchMicromachinesMicroorganismsMicroplasticsMineralsMiningModellingModernMathematicalPhysicsMolbankMoleculesMultimodalTechnologiesandInteractionMusclesNanoenergyAdvancesNanomanufacturingNanomaterialsNDTNetworkNeurogliaNeurologyInternationalNeuroSciNitrogenNon-CodingRNANursingReportsNutraceuticalsNutrientsObesitiesOceansOncoOpticsOralOrganicsOrganoidsOsteologyOxygenParasitologiaParticlesPathogensPathophysiologyPediatricReportsPetsPharmaceuticalsPharmaceuticsPharmacoepidemiologyPharmacyPhilosophiesPhotochemPhotonicsPhycologyPhyschemPhysicalSciencesForumPhysicsPhysiologiaPlantsPlasmaPlatformsPollutantsPolymersPolysaccharidesPopulationsPoultryPowdersProceedingsProcessesProsthesisProteomesPsychiatryInternationalPsychoactivesPsychologyInternationalPublicationsQuantumBeamScienceQuantumReportsQuaternaryRadiationReactionsRealEstateReceptorsRecyclingRegionalScienceandEnvironmentalEconomicsReligionsRemoteSensingReportsReproductiveMedicineResourcesRheumatoRisksRoboticsRuminantsSafetySciScientiaPharmaceuticaSclerosisSeedsSensorsSeparationsSexesSignalsSinusitisSmartCitiesSocialSciencesSociétéInternationaled’UrologieJournalSocietiesSoftwareSoilSystemsSolarSolidsSpectroscopyJournalSportsStandardsStatsStressesSurfacesSurgeriesSurgicalTechniquesDevelopmentSustainabilitySustainableChemistrySymmetrySynBioSystemsTargetsTaxonomyTechnologiesTelecomTextilesThalassemiaReportsTherapeuticsThermoTimeandSpaceTomographyTourismandHospitalityToxicsToxinsTransplantologyTraumaCareTrendsinHigherEducationTropicalMedicineandInfectiousDiseaseUniverseUrbanScienceUroVaccinesVehiclesVenereologyVeterinarySciencesVibrationVirtualWorldsVirusesVisionWasteWaterWildWindWomenWorldWorldElectricVehicleJournalYouthZoonoticDiseasesSubscribe©1996-2024MDPI(Basel,Switzerland)unlessotherwisestatedDisclaimerDisclaimer/Publisher’sNote:Thestatements,opinionsanddatacontainedinallpublicationsaresolelythoseoftheindividualauthor(s)andcontributor(s)andnotofMDPIand/ortheeditor(s).MDPIand/ortheeditor(s)disclaimresponsibilityforanyinjurytopeopleorpropertyresultingfromanyideas,methods,instructionsorproductsreferredtointhecontent.TermsandConditionsPrivacyPolicyWeusecookiesonourwebsitetoensureyougetthebestexperience.Readmoreaboutourcookieshere.AcceptBacktoTopTop//oldbrowserfix-thiswaytheconsolelogrowswon'tthrow(silent)errorsinbrowsersnotsupportingconsolelogif(!window.console)window.console={};if(!window.console.log)window.console.log=function(){};varcurrentJournalNameSystem="none";$(document).ready(function(){$('select.foundation-select').multiselect({search:true,minHeight:130,maxHeight:130,});$(document).foundation({orbit:{timer_speed:4000,},reveal:{animation:'fadeAndPop',animation_speed:100,}});$(".chosen-select").each(function(element){varmaxSelected=(undefined!==$(this).data('maxselectedoptions')?$(this).data('maxselectedoptions'):100);$(this).on('chosen:ready',function(event,data){varselect=$(data.chosen.form_field);if(select.attr('id')==='journal-browser-volume'){$(data.chosen.dropdown).addClass('UI_JournalBrowser_Volume_Options');}if(select.attr('id')==='journal-browser-issue'){$(data.chosen.dropdown).addClass('UI_JournalBrowser_Issue_Options');}}).chosen({display_disabled_options:false,disable_search_threshold:7,max_selected_options:maxSelected,width:"100%"});});$(".toEncode").each(function(e){varoldHref=$(this).attr("href");varnewHref=oldHref.replace('.botdefense.please.enable.jascript.','@');$(this).attr("href",newHref);if(!$(this).hasClass("emailCaptcha")){$(this).html(newHref.replace('mailto:',''));}$(this).removeClass("visibility-hidden");});$(document).on('opened.fndtn.reveal','[data-reveal]',function(){$(document).foundation('equalizer','reflow');});//fixtheimesthathetheight/widthdefined//otherwisethedefaultfoundationstylesoverwritethetdefinitions$("img").each(function(){if($(this).attr('width')!=undefined||$(this).attr('height')!=undefined){$(this).addClass("img-fixed");}});$("#basic_search,#advanced_search").submit(function(e){varsearchArguments=false;$(this).find("input,select").not("#search,.search-button").each(function(){if(undefined===$(this).val()||""===$(this).val()){$(this).attr('name',null);}else{$(this).attr('name');searchArguments=true;}});if(!searchArguments){window.location=$(this).attr('action');returnfalse;}});$(".hide-show-desktop-option").click(function(e){e.preventDefault();varparentDiv=$(this).closest("div");$.ajax({url:$(this).attr('href'),success:function(msg){parentDiv.removeClass().hide();}});});$(".generic-toggleable-header").click(function(e){$(this).toggleClass("active");$(this).next(".generic-toggleable-content").toggleClass("active");});/**handlewholerowasalinkiftherowcontainsonlyonevisiblelink*/$("table.newtr").hover(function(){if($(this).find("td:visiblea").length==1){$(this).addClass("single-link");}},function(){$(this).removeClass("single-link");});$("table.new:not(.table-of-tables)").on("click","tr.single-link",function(e){vartarget=$(e.target);if(!e.ctrlKey&&!target.is("a")){$(this).find("td:visiblea")[0].click();}});$(document).on("click",".custom-accordion-for-small-screen-link",function(e){if($(this).closest("#basic_search").length>0){if($(".search-container__advanced").first().is(":visible")){openAdvanced()}}if(Foundation.utils.is_small_only()){if($(this).hasClass("active")){$(this).removeClass("active");$(this).next(".custom-accordion-for-small-screen-content").addClass("show-for-medium-up");}else{$(this).addClass("active");$(this).next(".custom-accordion-for-small-screen-content").removeClass("show-for-medium-up");$(document).foundation('orbit','reflow');}}if(undefined!==$(this).data("callback")){varcustomCallback=$(this).data("callback");func=window[customCallback];func();}});$(document).on("click",".js-open-small-search",function(e){e.preventDefault();$(this).toggleClass("active").closest(".tab-bar").toggleClass("active");$(".search-container").toggleClass("hide-for-small-down");});$(document).on("click",".js-open-menu",function(e){$(".search-container").addClass("hide-for-small-down");});$(window).on('resize',function(){recalculate_main_browser_position();recalculate_responsive_moving_containers();});updateSearchLabelVisibilities();recalculate_main_browser_position();recalculate_responsive_moving_containers();if(window.document.documentMode==11){$("",{rel:"stylesheet",type:"text/css",href:"fonts.googleapis.com/icon?family=Material+Icons"}).appendTo("head");}});functionrecalculate_main_browser_position(){if(Foundation.utils.is_small_only()){if($("#js-main-top-container").parent("#js-large-main-top-container").length>0){$("#js-main-top-container").appendTo($("#js-small-main-top-container"));}}else{if($("#js-main-top-container").parent("#js-small-main-top-container").length>0){$("#js-main-top-container").appendTo($("#js-large-main-top-container"));}}}functionrecalculate_responsive_moving_containers(){$(".responsive-moving-container.large").each(function(){varpreviousParent=$(".responsive-moving-container.active[data-id='"+$(this).data("id")+"']");varmovingContent=previousParent.html();if(Foundation.utils.is_small_only()){varcurrentParent=$(".responsive-moving-container.small[data-id='"+$(this).data("id")+"']");}elseif(Foundation.utils.is_medium_only()){varcurrentParent=$(".responsive-moving-container.medium[data-id='"+$(this).data("id")+"']");}else{varcurrentParent=$(".responsive-moving-container.large[data-id='"+$(this).data("id")+"']");}if(previousParent.attr("class")!==currentParent.attr("class")){currentParent.html(movingContent);previousParent.html();currentParent.addClass("active");previousParent.removeClass("active");}});}//cookiesallowedischeckedfroma)localstoreandb)fromserverseparatelysothatthefooterbardoesn't//getincludedinthecustompecachesfunctioncheckCookiesAllowed(){varcookiesEnabled=localStore.getItem("mdpi_cookies_enabled");if(null===cookiesEnabled){$.ajax({url:"/ajax_cookie_value/mdpi_cookies_accepted",success:function(data){if(data.value){localStore.setItem("mdpi_cookies_enabled",true);checkDisplaySurvey();}else{$(".js-allow-cookies").show();}}});}else{checkDisplaySurvey();}}functioncheckDisplaySurvey(){}window.addEventListener('CookiebotOnAccept',function(e){varCookieDate=newDate;if(Cookiebot.consent.preferences){CookieDate.setFullYear(CookieDate.getFullYear()+1);document.cookie="mdpi_layout_type_v2=mobile;path=/;expires="+CookieDate.toUTCString()+";";$(".js-toggle-desktop-layout-link").css("display","inline-block");}},false);window.addEventListener('CookiebotOnDecline',function(e){if(!Cookiebot.consent.preferences){$(".js-toggle-desktop-layout-link").hide();if(""==="desktop"){window.location="/toggle_desktop_layout_cookie";}}},false);varhash=$(location).attr('hash');if("#share"===hash){if(1===$("#main-share-modal").length){$('#main-share-modal').foundation('reveal','open');}} varmainColumn1="#middle-column";varurl="/ajax_journals_by_subject/__subject_id__"; $(function(){recalculate_journal_ime_heights();//addresizeendeventforthewindow(torecalculatesidecolumnelements)//TODO:isitbettertouseresizeendorresizehere?$(window).on('resize',function(){mdpi_column_height_module.calculateColumnHeights(false,mainColumn1);$("#index-journalsimg").css("height","auto");recalculate_journal_ime_heights();});$("a.link-browse-by").click(function(e){e.preventDefault();$(this).find('span').toggle();$("#index-journalsimg").css("height","50px");$(this).next('ul').toggleClass('hidden',function(){$(window).trigger('resize');});if($(this).hasClass('link-browse-by__indexing')){$(this).toggleClass('UI_BrowseIndexing_Closed');$(this).toggleClass('UI_BrowseIndexing_Opened');}if($(this).hasClass('link-browse-by__subject')){$(this).toggleClass('UI_BrowseSubject_Closed');$(this).toggleClass('UI_BrowseSubject_Opened');}});$(".js-journals-by-subjects-container").on("change","select",function(e){$(".js-journals-by-subjects-containera[data-subjectid='"+$(this).val()+"']").click();});$(".js-journals-by-subjects-container").on("click","a.journal-browse-link",function(e){e.preventDefault();varsubjectId=$(this).data("subjectid");varelement=$('#journal-listing.slider-container.subject_'+subjectId);$('#journal-listing.slider-container').hide();element.show();$(this).closest("ul").find("li").removeClass("active");$(this).closest("li").addClass("active");if(!element.hasClass("loaded")){varajaxUrl=url.replace(/__subject_id__/g,subjectId);$.ajax({url:ajaxUrl,success:function(msg){element.html(msg.data);element.addClass("loaded");$(document).foundation();$(document).foundation('orbit','reflow');}});}else{$(document).foundation('orbit','reflow');}});$(".hero-containerul").removeClass("hidden");$(".js-journals-by-subjects-container.side-menu-li.activea.journal-browse-link").click();});functionrecalculate_journal_ime_heights(){varcandidates=$("#index-journalsimg");varsmallest=candidates.first()$(candidates).each(function(index,element){if($(element).height()!function(e,t,n,s,u,a){e.twq||(s=e.twq=function(){s.exe?s.exe.apply(s,arguments):s.queue.push(arguments);},s.version='1.1',s.queue=[],u=t.createElement(n),u.async=!0,u.src='//static.ads-twitter.com/uwt.js',a=t.getElementsByTName(n)[0],a.parentNode.insertBefore(u,a))}(window,document,'script');//InsertTwitterPixelIDandStandardEventdatabelowtwq('init','o2pip');twq('track','PeView');